lunes, 8 de septiembre de 2014

Human nutrition and health


1. What is nutrient?

  Nutrient is a chemical substance found in foods and used in the human body. Nutrients gives you energy, strengthen your bones and muscles and even protect you from getting disease. There are two different types of nutrients that you must be aware of: essential nutrient and non-essential nutrient


  Essential nutrients are the nutrients that cannot be synthesized by your body and thus has to be consumed from food intake. On the other hand, there is a few nutrients that are not essential. Non essential nutrients can be synthesized in the body from other nutrients or found from alternative sources. Yet, if they are involved in diet, the need for biosynthesis of non essential nutrients is diminished.

Essential nutrients
Non-essential nutrients
1.         Water
2.         Some of fatty acids
e.g. omega-3 linoleic acid and omega-6 linoleic acid
3.         Some vitamins
e.g. A, some B vitamins, C, D, folate
4.        Dietary minerals
e.g. iron, potassium, sodium, calcium, phosphorous and iodine
5.         Some amino acids
e.g. phenylalanine and methionine
6.         Carbohydrates
(but energy can come from other sources such as lipids and proteins)
7.         Other lipids and fatty acids
8.         Other vitamins
9.         Other minerals
10.       Other amino acids






  Then how are the non-essential nutrients synthesized in the body? Out of twenty different amino acids, eleven of them are non essential meaning they can be synthesized in the body from other nutrients. Yet, the human body will only expend the energy required for their biosynthesis if they cannot be derived from the diet.

*Biosynthesis: production of non essential nutrients in the body from components of essential nutrients

2. Protein deficiency malnutrition

Protein deficiency malnutrition is caused by inadequate supply of one or more essential amino acids and it is the key factor of ‘kwashiorkor’.  The disease is most frequently found in children and infants in Africa and Central America. It is especially common in developing countries that are experiencing famine, political unrest and natural disasters. Consequences of Kwashiorkor include stunted growth, muscle and skin problems, impaired mental problems, immune system impairment, oedema.





(Oedema is a swell of abdomen and legs as plasma proteins responsible for controlling the tissue fluid are not projected and thus fluids build up.)




3. Phenylketonuria(PKU)

  Phenylketonuria(PKU) is a genetic mutation changes of the gene coding for tyrosine hydroxylase which is responsible for metabolizing phenylalanine in to tyrosine. Phenylalanine is instead converted into phenyl pyruvic acid; resulting in a high level of ketones in the blood and urine. Over time, this may result in brain damage or mental retardation.

  Diagnosis of phenylketonuria can be made by a simple blood test for the levels of phenylalanine. As PKU results in the build up of phenylalanine in the bloodstream, it is treated by following a special diet that is low in protein.
Diet should include fruits, grains, vegetables and special formula milk and must be undertaken from early in life or else symptoms will appear. Symptoms may include tremors, seizures, eczema, skin rashes and eventually brain damage (mental retardation)





4. Fatty acids

  Fatty acids all have the same general structure, but there maybe variation in the bonding between carbon atoms. Saturated fatty acids have no carbon double bonds while unsaturated fatty acids do have some double bonds between carbon atoms. The unsaturated fatty acids can be divided into mono-saturated with single double bond and poly-saturated with multiple double bonds. There is another variation as well: cis-isomers that hydrogen attached to the double bonded atoms are on the same side and trans-isomers that have hydrogen on opposite sides.

  All types of fatty acids consumed as part of dietary intake will cause weight gain and increase risks of hear disease if taken in excessive amounts. There are several different health effects of consuming different types of fatty acids explained below.







Saturated fatty acids
Unsaturated fatty acids



Cis-fats
Trans-fats
Sources
Animal fats, butter, milk, cheese
Vegetable oils, fish oils
Hydrogenated vegetable oils, margarine
Effects
1.         Raise harmful LDL cholesterol
2.         Leads to atherosclerosis and coronary heart disease(CHD)
3.         Promotes beneficial HDL cholesterol
4.        Inhibits harmful LDL cholesterol
5.         Omega-3 linked to brain development
6.         Significantly raises LDL cholesterol
7.         Strong links to atherosclerosis and CHD













Bibliography






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